⚡ Index-Expert™ #14 — Bioactive peptidome, functional health and clinical vigilance • Enzyme peptidique clé de digestibilité et d'anti-amertume
🔎 Proof & primary source (idx14:enzyme-pepx-hydrolyse-bcm7)
X-prolyl dipeptidyl aminopeptidase (PepX) — BCM-7 Hydrolysis
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
🧀 155 concerned cheese(s) & family(ies) •
🦠 24 linked living taxon(s)
🔬 Biochemical mechanism & vector
Gène : pepX (EC 3.4.14.11) • Dégrade la β-casomorphine-7 et réduit l'amertume des pâtes.
📚 Scientific references & traceability
UniProtKB:P22346 🔎 • UniProtKB:A2RNK1 🔎 • UniProtKB:A8YVY9 🔎 • UniProtKB:B4U108 🔎 • UniProtKB:B9DVM1 🔎 • UniProtKB:C0MAI3 🔎 • UniProtKB:P40334 🔎 • UniProtKB:Q02W78 🔎 • UniProtKB:Q038E8 🔎 • UniProtKB:Q03H46 🔎 • UniProtKB:Q03J44 🔎 • HAL:tel-01923777 • UniProtKB:Q03PM5 🔎 • UniProtKB:Q049K4 🔎 • UniProtKB:Q1G9E8 🔎 • UniProtKB:Q1WRZ1 🔎 • UniProtKB:Q59485 🔎 • HAL-INRAE:hal-01454507 🔎 (DOI:10.1016/S0958-6946(02)00081-X) 🔎 • HAL-INRAE:hal-01454506 🔎 (DOI:10.1016/S0958-6946(02)00051-1) 🔎 • UniProtKB:Q5LYA9 🔎 • UniProtKB:Q5M2X3 🔎 • UniProtKB:Q88YC0 🔎 • UniProtKB:Q8GMC0 🔎 • HAL-INRAE:hal-01454506 🔎 (DOI:10.1016/S0958-6946(02)00051-1) 🔎 • HAL-INRAE:hal-01209298 🔎 (DOI:10.1016/j.fm.2011.09.009) 🔎 • UniProtKB:Q8L376 🔎 • HAL:inserm-00978580 (DOI:10.1186/1471-2164-15-272) 🔎 • HAL-INRAE:hal-01204464 🔎 (DOI:10.1371/journal.pone.0116337) 🔎
🧀 Associated cheeses & dairy matrices (155)
🧀 Fourme d'Ambert cheese from cow's milk
Via Lactococcus cremoris (pepX)
🧀 Brie de Meaux cheeses
Via Lactococcus cremoris (pepX)
🧀 Gouda
Via Lactococcus cremoris (pepX)
🧀 Cheddar cheese
Via Lactococcus cremoris (pepX)
🧀 Le Riopelle de l'Isle
Via Lactococcus cremoris (pepX)
🧀 Bleu bénédictin
Via Lactococcus cremoris (pepX)
🧀 Paillasson de l'Isle d'Orléans
Via Lactococcus cremoris (pepX)
🧀 Fromage en grains
Via Lactococcus cremoris (pepX)
🧀 Uncooked pressed cheeses
Via Lactococcus cremoris (pepX)
🧀 Whey
Via Lactococcus cremoris (pepX)
🧀 Asiago
Via Lactococcus cremoris (pepX)
🧀 Pecorino
Via Lactococcus cremoris (pepX)
🧀 Fiore sardo
Via Lactococcus cremoris (pepX)
🧀 Pecorino toscano
Via Lactococcus cremoris (pepX)
🧀 Castelmagno
Via Lactococcus cremoris (pepX)
🧀 Provolone del monaco
Via Lactococcus cremoris (pepX)
🧀 Kefir
Via Lactococcus cremoris (pepX)
🧀 Monte veronese
Via Lactococcus cremoris (pepX)
🧀 Provolone
Via Lactococcus cremoris (pepX)
🧀 Caciotta
Via Lactococcus cremoris (pepX)
🧀 Caciocavallo
Via Lactococcus cremoris (pepX)
🧀 Cheddar cheese
Via Lactococcus cremoris (pepX)
🧀 Edam
Via Lactococcus cremoris (pepX)
🧀 Blue cheese
Via Lactococcus cremoris (pepX)
🧀 Tomme cheese from cow's milk
Via Lactococcus cremoris (pepX)
🦠 Linked living organisms & NCBI taxa (24)
Lactococcus cremoris
#1359
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:P22346)
Lactococcus cremoris subsp. cremoris MG1363
#416870
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:A2RNK1)
Lactobacillus helveticus DPC 4571
#405566
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:A8YVY9)
Streptococcus equi subsp. zooepidemicus MGCS10565
#552526
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:B4U108)
Streptococcus uberis 0140J
#218495
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:B9DVM1)
Streptococcus equi subsp. equi 4047
#553482
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:C0MAI3)
Lactobacillus delbrueckii subsp. lactis
#29397
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:P40334)
Lactococcus cremoris subsp. cremoris SK11
#272622
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q02W78)
Lacticaseibacillus paracasei ATCC 334
#321967
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q038E8)
Pediococcus pentosaceus ATCC 25745
#278197
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q03H46)
Streptococcus thermophilus LMD-9
#322159
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q03J44)
Levilactobacillus brevis ATCC 367
#387344
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q03PM5)
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
#321956
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q049K4)
Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002
#390333
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q1G9E8)
Ligilactobacillus salivarius UCC118
#362948
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q1WRZ1)
Lactobacillus helveticus
#1587
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q59485)
Streptococcus thermophilus CNRZ1066
#299768
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q5LYA9)
Streptococcus thermophilus LMG 18311
#264199
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q5M2X3)
Lactiplantibacillus plantarum WCFS1
#220668
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q88YC0)
Streptococcus thermophilus
#1308
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q8GMC0)
Streptococcus macedonicus
#59310
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q8L376)
Lactococcus lactis subsp. lactis Il1403
#272623
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q9CE01)
Lacticaseibacillus rhamnosus
#47715
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q9RDW6)
Lactobacillus delbrueckii subsp. bulgaricus
#1585
Xaa-Pro dipeptidyl-peptidase (Gène pepX, UniProt:Q9Z5K9)
🔮 Other concepts & symptoms in the same Index-Expert™ (48)
Nutritional Biomarker: Glutamic acid
(209🧀 / 99🦠)
Nutritional Biomarker: Leucine
(209🧀 / 99🦠)
Nutritional Biomarker: Proline
(203🧀 / 99🦠)
Nutritional Biomarker: Aspartic acid
(197🧀 / 95🦠)
Nutritional Biomarker: Folic acid
(191🧀 / 93🦠)
Nutritional Biomarker: Valine
(171🧀 / 99🦠)
Nutritional Biomarker: Lysine
(142🧀 / 87🦠)
Nutritional Biomarker: Vitamin D (D2 + D3), International Units
(79🧀 / 74🦠)
Nutritional Biomarker: Vitamin D3 (cholecalciferol)
(64🧀 / 70🦠)
Nutritional Biomarker: Vitamin A, RAE
(68🧀 / 66🦠)
Nutritional Biomarker: Carotene, alpha
(69🧀 / 58🦠)
Nutritional Biomarker: Carotene, beta
(67🧀 / 51🦠)
Nutritional Biomarker: Folate, DFE
(64🧀 / 50🦠)
Nutritional Biomarker: Cryptoxanthin, beta
(59🧀 / 54🦠)
Nutritional Biomarker: Lycopene
(56🧀 / 53🦠)
Nutritional Biomarker: Choline, total
(41🧀 / 57🦠)
Nutritional Biomarker: Vitamin C, total ascorbic acid
(42🧀 / 51🦠)
Nutritional Biomarker: Tocopherol, delta
(39🧀 / 52🦠)
Nutritional Biomarker: Isoleucine
(34🧀 / 50🦠)
Nutritional Biomarker: Vitamin K (Dihydrophylloquinone)
(32🧀 / 50🦠)
Nutritional Biomarker: Vitamin K (phylloquinone)
(39🧀 / 41🦠)
Nutritional Biomarker: Retinol
(42🧀 / 34🦠)
Nutritional Biomarker: Lutein + zeaxanthin
(29🧀 / 39🦠)
Functional Guild: Ferment lactique primaire
(55🧀 / 11🦠)
Nutritional Biomarker: Vitamin E (alpha-tocopherol)
(35🧀 / 18🦠)