Multidimensional architecture • Tyrodexia™ v11.0 knowledge graph
Official registry of scientific poles and Index-Experts™
Connected to the universal backdrop of life of the NCBI to evolve day by day, the Tyrodexia™ ecosystem connects the global and Québec cheese directory, biochemical and gastronomic profiles, the Authorized Cheesemaking Perimeter, the master starter core (#00) and the 16 inverted Index-Experts™.
🏛️ 1. Universal core of life & relational, gastronomic and biochemical architecture (9 poles)
NCBI 2026 Universal Backdrop
Universal master core of life (9 taxonomic, genomic and bibliographic poles)
✔ Active & certified
Valid scientific nomenclature
Historical synonyms & basionyms
International common names
Evolutionary phylogenetic tree
Strains & global culture collections
Biological substrates & hosts
RefSeq / GenBank genomic architecture
PubMed scientific literature
Authorized Cheesemaking Perimeter, USDA Biochemistry & FlavorGraph Pairings (9 tables)
Relational, gastronomic, nutritional & multilingual core of cheeses and living organisms
1 177 cheeses & matrices
• 46 557 active species & strains
• 46 557 routed TaxIDs
✔ Active & certified
1. World & Québec cheese directory (1 177)
2. Identities, terroirs, PDO/PGI & Awards (1 177)
3. Authorized Cheesemaking Perimeter & Lineages (54 755)
4. NPClassifier molecular ontology (1 760 sets)
5. Cheeses ↔ Organisms bridge (1 381 links)
6. Phages ↔ Host starters bridge (14 708 links)
7. Gastronomic pairings & bridge aromas (648)
8. Complete USDA biochemical profiles (664)
9. Multilingual indexing (140 232 terms)
🧀 2. Master starter core (#00) & the 16 inverted Index-Experts™
17 / 17 active and verified poles
Core #00
Tyrodexia™ Cheese Core
• 8 878 qualified records
Master index of cheese starters and ripening cultures
Proteolysis, lipolysis, texture, cellar parameters and curd ripening flora
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Dairy & cheese matrix
Technological aptitude & lineage
Molecular markers, proteome & collections
Official sources & reference book
Genomic & physiological parameters
PubMed literature & taxonomic history
Index-Expert™ #01
Tyrodexia™ Architecture
• 34 344 qualified records
Synonyms and historical names (NCBI)
Post-genomic concordance between historical nomenclatures and NCBI 2026 taxonomy
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Nomenclature concordance (NCBI)
Historical synonyms & basionyms
Taxonomic authority & reference strains
Official sources & reference book
Lineage & phylogenomic justification
PubMed taxonomic references
Index-Expert™ #02
Tyrodexia™ Architecture
• 8 876 qualified records
Ecological origins and habitats
Spruce shelves, resident barn biofilms, raw milks and cellar microclimates
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Cheese biotope & isolation substrates
Deposited strains & inoculation vector
Genomic & microclimatic parameters
Official sources & reference book
BioSample specimen & BioProject program
Ecology & PubMed references
Index-Expert™ #03
Tyrodexia™ Architecture
• 8 877 qualified records
Paste textures and rheology
Creaminess profile, paste suppleness, centripetal proteolysis and crystallogenesis
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Textural impact & enzymatic capacity
Proteolysis kinetics & metabolites
Lineage & common denomination
Official sources & reference book
Genomic markers & culture collections
PubMed rheological references
Index-Expert™ #04
Tyrodexia™ Architecture
• 8 878 qualified records
Cheese families and technologies
Cooked pressed, uncooked pressed, bloomy or washed-rind soft cheeses and blue cheeses
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Technological family & appellations
Taxonomic authority & denomination
Isolation substrates & collections
Official sources & reference book
Reference genomic metrics
PubMed cheese studies
Index-Expert™ #05
Tyrodexia™ Architecture
• 8 878 qualified records
Technological markers (pH and gas)
Vat acidification kinetics, redox potential and eye-forming gas release
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
GC% signature, metabolites & kinetics
Annotated proteome & lineage
Linked matrices, substrates & BioSample
Official sources & reference book
Genomic architecture & collections
PubMed scientific literature
Index-Expert™ #06
Tyrodexia™ Architecture
• 22 444 qualified records
Symptoms and manufacturing defects
Late butyric blowing, cat-hair mold, bitterness, cracks and rind mites
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Vigilance category & defect diagnosis
Taxonomic lineage & metabolites
Documented substrates & synonyms
Official sources & reference book
Genomic markers & detection strains
Operator safety & PubMed references
Index-Expert™ #07
Tyrodexia™ Architecture
• 14 262 qualified records
Bacteriophages and dairy virome
Lysogenic monitoring, 936/P335/c2 phages and natural starter strain rotation in vat
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Host spectrum & natural phage immunity
Viral proteins & taxonomy
NCBI authority & phage isolates
Official sources & reference book
Phage genomic architecture
Virome monitoring & PubMed references
Index-Expert™ #08
Tyrodexia™ Architecture
• 31 322 qualified records
Pathogens and bioprotection
Competitive exclusion in raw milk, anti-Listeria bacteriocins and food safety
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Official qualification & bioprotection
Isolation substrates & linked matrices
Official lineage, authority & synonyms
Official sources & reference book
Genomic markers & culture collections
Prophylaxis & PubMed references
Index-Expert™ #09
Tyrodexia™ Architecture
• 6 769 qualified records
Surface interactomes and syntrophy
Yeast-bacteria ecological successions, vitamin sharing and smear biofilms
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Surface consortia & deposited collections
Metabolites, pigments & proteome
Official lineage & denomination
Official sources & reference book
Genomic architecture & BioSample
Consortium balance & PubMed studies
Index-Expert™ #10
Tyrodexia™ Architecture
• 8 877 qualified records
Terroirs and protected designations (PDO/PGI)
Microbial and botanical signatures of world PDO/PGI specifications
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Appellations, terroirs & reference institute
Official lineage & taxonomic authority
Global collections & sequencing origin
Official sources & reference book
Reference genomic architecture
Terroir audit & PubMed references
Index-Expert™ #11
Tyrodexia™ Architecture
• 2 032 qualified records
Volatilome and aromatic profiles
Esters, methyl ketones, lactones, branched aldehydes and sulfur compounds (DMDS, methanethiol)
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Key aroma compounds & metabolites
Enzymatic proteome & lineage
Isolation substrate & synonyms
Official sources & reference book
Genomic architecture & collections
Aroma kinetics & PubMed studies
Index-Expert™ #12
Tyrodexia™ Architecture
• 6 677 qualified records
Affinage gestures and cellar care
Needling, dry brushing, smear washing, turning, salting and drying room airflow control
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Ripening matrices & cellar care
Characterized metabolites & proteome
Official lineage & NCBI authority
Official sources & reference book
Genomic architecture & collections
Cellar studies & PubMed references
Index-Expert™ #13
Tyrodexia™ Milk Science & Health
• 146 qualified records
Dairy mammals, breeds and casein polymorphism (A1/A2)
β-casein genetics (A1/A2 and BCM-7), κ-casein variants (AA/BB), heritage breeds and milk physicochemistry
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Dairy profile, linked cheeses & common name
Mammalian lineage & NCBI authority
Annotated proteome & metabolites
Subspecies, breeds & NCBI synonyms
Dairy species genomic architecture
PubMed scientific literature
Official sources & reference book
Index-Expert™ #14
Tyrodexia™ Milk Science & Health
• 6 667 qualified records
Bioactive peptidome, functional health and clinical vigilance
BCM-7 degradation by PepX enzyme, antihypertensive VPP/IPP tripeptides, GABA, vitamin K2, lactose and biogenic amines
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Nutraceutical activity & bioactive metabolites
Enzymatic proteome (PepX) & lineage
Cheese matrices & isolation substrates
Genomic & plasmid architecture
Reference collections & synonyms
PubMed scientific literature
Official sources & reference book
Index-Expert™ #15
Tyrodexia™ Pastoral Ecology
• 339 qualified records
Alpine pasture botany, natural meadows and terpene transfer
Mountain forage flora, transfer of monoterpenes, sesquiterpenes, β-carotene and omega-3 / CLA fatty acids to raw milk
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Phytochemical signature & terpenes (LOTUS)
Botanical lineage & NCBI authority
Plant proteome & botanical synonyms
Linked alpine cheeses & herbaria
Genomic architecture & replicons
PubMed scientific literature
Official sources & reference book
Index-Expert™ #16
Tyrodexia™ Living Materials & Engineering
• 612 qualified records
Plant coagulants, clotting enzymes and cellar wood species
Plant rennets (Cynara thistle, fig, Calotropis, Withania), fungal coagulases and cellar woods (spruce, fir, beech, chestnut)
Analytical dimensions covered:
NCBI TaxID identifier
Valid scientific name
Wood species or coagulant & lineage
Phytochemicals, resins & tannins
Annotated proteins/enzymes & synonyms
Linked cheeses, substrates & collections
Genomic architecture & replicons
PubMed scientific literature
Official sources & reference book